Security analysis of NIST-LWC contest finalists

Dissertação de mestrado integrado em Informatics EngineeringTraditional cryptographic standards are designed with a desktop and server environment in mind, so, with the relatively recent proliferation of small, resource constrained devices in the Internet of Things, sensor networks, embedded systems, and more, there has been a call for lightweight cryptographic standards with security, performance and resource requirements tailored for the highly-constrained environments these devices find themselves in. In 2015 the National Institute of Standards and Technology began a Standardization Process in order to select one or more Lightweight Cryptographic algorithms. Out of the original 57 submissions ten finalists remain, with ASCON and Romulus being among the most scrutinized out of them. In this dissertation I will introduce some concepts required for easy understanding of the body of work, do an up-to-date revision on the current situation on the standardization process from a security and performance standpoint, a description of ASCON and Romulus, and new best known analysis, and a comparison of the two, with their advantages, drawbacks, and unique traits.Os padrões criptográficos tradicionais foram elaborados com um ambiente de computador e servidor em mente. Com a proliferação de dispositivos de pequenas dimensões tanto na Internet of Things, redes de sensores e sistemas embutidos, apareceu uma necessidade para se definir padrões para algoritmos de criptografia leve, com prioridades de segurança, performance e gasto de recursos equilibrados para os ambientes altamente limitados em que estes dispositivos operam. Em 2015 o National Institute of Standards and Technology lançou um processo de estandardização com o objectivo de escolher um ou mais algoritmos de criptografia leve. Das cinquenta e sete candidaturas originais sobram apenas dez finalistas, sendo ASCON e Romulus dois desses finalistas mais examinados. Nesta dissertação irei introduzir alguns conceitos necessários para uma fácil compreensão do corpo deste trabalho, assim como uma revisão atualizada da situação atual do processo de estandardização de um ponto de vista tanto de segurança como de performance, uma descrição do ASCON e do Romulus assim como as suas melhores análises recentes e uma comparação entre os dois, frisando as suas vantagens, desvantagens e aspectos únicos

Visual outcomes after endoscopic pituitary adenomas surgery: our experience

Background: Pituitary adenomas are the most common cause of sellar tumors after the third decade of life. They can lead to visual impairment due to a close anatomical relationship with the optic chiasm. The purpose of this study is to evaluate visual outcomes after endoscopic pituitary adenoma surgery in patients from Egas Moniz hospital between January 2013 and August 2020. Material and methods: Patients with pituitary adenoma with pre- and post-surgical ophthalmological evaluation were retrospectively included. Pre- and post-surgical visual parameters, clinical, imaging, histological, and surgical data were selected, and a descriptive analysis was performed. Pre- and post-surgical visual parameters were compared using Statistical Package for the Social Sciences (SPSS). Improvement criteria were defined: pre-surgical visual complaints > post-surgical visual complaints; visual acuity (VA) (LogMAR) pre-surgical > VA (LogMAR) post-surgical; pre-surgical chromatic vision > post-surgical chromatic vision; visual field mean sensitivity (MS) post-surgical > visual field MS pre-surgical + 1; visual field temporal mean sensitivity (MST) post-surgical > visual field MST pre-surgical + 1; visual field nasal mean sensitivity (MSN) post-surgical > visual field MSN pre-surgical + 1. Results and Discussion: Of the total 18 patients included, 11 (68.8%) fulfilled all improvement criteria, and 14 (82.4%) fulfilled at least one. These results go with the current scientific evidence that pituitary adenoma resection in patients with pre-surgical visual symptoms considerably improves these symptoms. Conclusion: Standardization of visual evaluation may be a key point to identify prognostic factors for visual functionrecovery after surgery

Nutrition education in portuguese medical students: impact on the attitudes and knowledge

Nutrition has been underrepresented in the curriculum of many medical schools and therefore physicians do not feel adequately prepared to provide dietary counselling. The aim of the present study is to determine the impact of a Nutrition and Metabolism curricular unit on nutrition attitudes, knowledge and confidence on future clinical practice of medical students.info:eu-repo/semantics/publishedVersio

EVALUATION OF AN HPHT UNIT COUPLED WITH NIR PROBE TO DETERMINE ASPHALTENES PRECIPITATION ONSET UNDER DIFFERENT PRESSURES

Asphaltenes are characterized as the crude oil fraction with the highest molar mass and polarity, presetting mainly (poly) aromatic groups. The flocculation and deposition of asphaltenes causes large losses to the oil industry. Understanding the phase behavior of asphaltenes under conditions closer to those found in reservoirs is important. Therefore, LMCP/UFRJ started operating a high-pressure high-temperature (HPHT) unit coupled to a near-infrared spectrometer probe that can use different flocculants. This work describes the development of a procedure as well as the validation of the results obtained from this unit. Due to the complex composition of crude oil, model systems (MS) were prepared with asphaltenes extracted with n-pentane (C5I) and n-heptane (C7I). The experiments were carried out at atmospheric pressure, titrated with n-heptane, and at 100 and 300 bar titrated with propane. As expected, C7I asphaltenes were more unstable, presenting lower precipitation onset than C5I asphaltenes under ambient conditions and higher pressures. However, for both MS, the stability increased with rising pressure when using propane as a solvent. The proposed method to evaluate asphaltenes precipitation onset was effective for MS in toluene and dead crude oil, and is a promising alternative for investigation of different types of crude oil

A robótica educacional no ensino de Química, elaboração, construção e aplicação de um robô imóvel no ensino de conceitos relacionados à tabela periódica

ESSE TRABALHA APRESENTA A ELABORAÇÃO, DESENVOLVIMENTO E APLICAÇÃO DE UM ROBÔ DO TIPO IMÓVEL, CHAMADO ROBÔ IMÓVEL TABELA PERIÓDICA (RITP). O RESULTADO É UMA TABELA PERIÓDICA INTERATIVA QUE PRETENDE OFERECER AO PROFESSOR A OPORTUNIDADE DE ORIENTAR OS ALUNOS A CONSTRUIR O CONCEITO DE FORMA CONJUNTA, DESENVOLVENDO-O A PARTIR DE INFORMAÇÕES FUNDAMENTAIS QUE ENVOLVEM CONCEITOS BÁSICOS DAS DIFERENTES ÁREAS DO CONHECIMENTO, SENDO ELES QUÍMICOS, FÍSICOS E MATEMÁTICOS E DE LÓGICA COMPUTACIONAL. O RITP FOI DESENVOLVIDO EM 6 MESES, UTILIZANDO MATERIAIS DE FÁCIL ACESSO E DE BAIXO CUSTO. SUA INTERFACE PODE SER CONTROLADA POR UM SOFTWARE LIVRE, CHAMADO LOGO. NOTAMOS NO TRABALHO QUE O RITP PODE PROPORCIONAR UMA NOVA FORMA DE AVALIAR OS ALUNOS, CRIANDO UM AMBIENTE DESCONTRAÍDO E DE COOPERAÇÃO PARA QUE OS ESTUDANTES POSSAM SE DIVERTIR EM GRUPOS, EXPLORANDO AS POTENCIALIDADES PRESENTES NA ROBÓTICA EDUCACIONAL

Portuguese Football Federation consensus statement 2020: nutrition and performance in football

Nutrition is an undeniable part of promoting health and performance among football (soccer) players. Nevertheless, nutritional strategies adopted in elite football can vary significantly depending on culture, habit and practical constraints and might not always be supported by scientific evidence. Therefore, a group of 28 Portuguese experts on sports nutrition, sports science and sports medicine sought to discuss current practices in the elite football landscape and review the existing evidence on nutritional strategies to be applied when supporting football players. Starting from understanding football's physical and physiological demands, five different moments were identified: preparing to play, match-day, recovery after matches, between matches and during injury or rehabilitation periods. When applicable, specificities of nutritional support to young athletes and female players were also addressed. The result is a set of practical recommendations that gathered consensus among involved experts, highlighting carbohydrates periodisation, hydration and conscious use of dietary supplements.info:eu-repo/semantics/publishedVersio

Patient-physician discordance in assessment of adherence to inhaled controller medication: a cross-sectional analysis of two cohorts

We aimed to compare patient's and physician's ratings of inhaled medication adherence and to identify predictors of patient-physician discordance.(SFRH/BPD/115169/2016) funded by Fundação para a Ciência e Tecnologia (FCT); ERDF (European Regional Development Fund) through the operations: POCI-01-0145-FEDER-029130 ('mINSPIRERS—mHealth to measure and improve adherence to medication in chronic obstructive respiratory diseases—generalisation and evaluation of gamification, peer support and advanced image processing technologies') cofunded by the COMPETE2020 (Programa Operacional Competitividade e Internacionalização), Portugal 2020 and by Portuguese Funds through FCT (Fundação para a Ciência e a Tecnologia).info:eu-repo/semantics/publishedVersio

EAIR 41st Annual Forum in Leiden, The Netherlands 25 till 28 August 2019

Trabalho apresentado em EAIR 41st Annual Forum, 25-28 agosto 2019, Leiden, Países Baixos.Polytechnic Institutes in Portugal: research on the impact of twelve institutes on the local economy Higher Education Institutions are recognized as important actors in regional development. The Portuguese higher education system comprises both Universities and Polytechnic Institutes, which face an increasing pressure to demonstrate that their presence has an impact on the surrounding communities contributing to their economic development. This paper presents the estimation of the economic impact of twelve Polytechnic Institutes, located in quite diverse regions, based on a shared model so that comparisons have a collective framework of analysis. The main results obtained show that the economic impact ranged from 1.8% to 10.6% of the local GDP and that these Institutes are major local employers.info:eu-repo/semantics/publishedVersio

Comparative Effectiveness of COVID-19 Vaccines in Preventing Infections and Disease Progression from SARS-CoV-2 Omicron BA.5 and BA.2, Portugal

We estimated comparative primary and booster vaccine effectiveness (VE) of SARS-CoV-2 Omicron BA.5 and BA.2 lineages against infection and disease progression. During April-June 2022, we implemented a case-case and cohort study and classified lineages using whole-genome sequencing or spike gene target failure. For the case-case study, we estimated the adjusted odds ratios (aORs) of vaccination using a logistic regression. For the cohort study, we estimated VE against disease progression using a penalized logistic regression. We observed no reduced VE for primary (aOR 1.07 [95% CI 0.93-1.23]) or booster (aOR 0.96 [95% CI 0.84-1.09]) vaccination against BA.5 infection. Among BA.5 case-patients, booster VE against progression to hospitalization was lower than that among BA.2 case-patients (VE 77% [95% CI 49%-90%] vs. VE 93% [95% CI 86%-97%]). Although booster vaccination is less effective against BA.5 than against BA.2, it offers substantial protection against progression from BA.5 infection to severe disease.The acquisition of sequencing equipment and reagents used in this study by the Instituto Nacional de Saúde Doutor Ricardo Jorge was partially funded by the HERA project (grant no. 2021/PHF/23776) supported by the European Commission through the European Centre for Disease Control, and also partially funded by the GenomePT project (grant no. POCI-01-0145-FEDER-022184), supported by COMPETE 2020–Operational Programme for Competitiveness and Internationalisation, Lisboa Portugal Regional Operational Programme, Algarve Portugal Regional Operational, under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund, and by the Portuguese Science and Technology Foundation. Algarve Biomedical Center Laboratory received public funding through the Project ALG-D2-2021-06 Variants Screen in Southern Portugal– Monitoring Variants of Concern in Southern Portugal and the Portuguese Science and Technology Foundation national support through the Comprehensive Health Research Center (grant no. UIDP/04923/2020)info:eu-repo/semantics/publishedVersio

THOR is a targetable epigenetic biomarker with clinical implications in breast cancer

Breast cancer (BC) is the most frequently diagnosed cancer and a leading cause of death among women worldwide. Early BC is potentially curable, but the mortality rates still observed among BC patients demon‑ strate the urgent need of novel and more efective diagnostic and therapeutic options. Limitless self-renewal is a hallmark of cancer, governed by telomere maintenance. In around 95% of BC cases, this process is achieved by telom‑ erase reactivation through upregulation of the human telomerase reverse transcriptase (hTERT). The hypermethylation of a specifc region within the hTERT promoter, termed TERT hypermethylated oncological region (THOR) has been associated with increased hTERT expression in cancer. However, its biological role and clinical potential in BC have never been studied to the best of our knowledge. Therefore, we aimed to investigate the role of THOR as a biomarker and explore the functional impact of THOR methylation status in hTERT upregulation in BC.info:eu-repo/semantics/publishedVersio